InnoScan Scanners

Products - Microarray Instruments - InnoScan Scanners

The new ArrayIt® InnoScan® 700 microarray scanner is the fastest high-resolution 1 or 2 color confocal fluorescent microarray scanner available. Dual detection channels allow two-color scanning of an entire glass substrate slide at 10 micron resolution in approximately minutes. Scanning resolution is adjustable between 3 and 40 microns, making it perfect for both ex-situ and high-density in-situ manufactured microarrays. Dynamic auto focusing guantees uniform scanning across the entire chip surface. Mapix® Software allows real-time adjustment of scanning intensity, easy channel balancing, data quantitation and data export. This network compatible Windows and Linux system is the most compact laser scanner on the market and weighs just over 10 kg.

Specifications:

Lasers

Thermoelectrically cooled laser diodes with stabilized feedback output

Excitation wavelength

635 nm and 532 nm (700A model)
635 nm (700R model)
532 nm (700G model)

Laser power

Adjustable (2 laser power settings available)

Autofocus

Real-time and automated

Detection

True confocal and high performances digital Laser/PMT system

Optical resolution

2.4 micron

Pixel size

3 µm to 40 µm

Scanning time

3.5 min per 22 x 70 mm substrate at 10 µm resolution

Scan area:

Full substrate (22 x 70 mm)

Scanning area

22 x 70 mm

Image format

Standard TIFF (16 bits gray scale)

Barcode reader

All formats

Power supply

88 - 264 VAC

Dimension

25 x 45 x 35 cm (L x D x H)

10 x 18 x 14 ” (L x D x H)

Weight

12 Kg (26 lbs)

Class

Class I laser product

Sensitivity

0.1 fluor/µm²

Dynamic range

>10,000-fold

Uniformity

<5% CV

Sample

All standard glass substrate slides (25 x 76 mm)

Computer interface

Ethernet

Image analysis

Highly accurate grid positioning using automatic spot recognition provide accurate quantification and 16-bit exportable TIFF data

Compatible fluorophores:

Cy5, Alexa 647, Alexa 660 (635 nm); Cy3, Alexa 546, Alexa 555 (532 nm); and custom wavelenghts available

Figure 1. The ArrayIt® InnoScan® 700 microarray scanner uses dynamic auto focusing, which greatly reduces background noise and increases signal intensities. This proprietary auto-focusing technology allows the system to adjust to temperature changes, mechanical perturbations and other system changes that would otherwise cause fluctuations in signal and background. The result is highly uniform scanning across the entire chip surface and consistent performance scan after scan.

Quantitation and analysis software is included with every scanner:
Mapix® is a microarray image analysis software application that is both intuitive and easy to use, combining imaging and analysis tools for superior performance.

Highly efficient algorithms provide rapid and effective feature gridding through automatic spot searching and optimal grid alignment.

Automatic spot segmentation ensures high-quality experiment data by selecting relevant pixels and eliminating unwanted ones.
Gridding performance and quantification process are adapted to the high resolution of the InnoScan700 (3m) and therefore to the size of images generated.
Optimal data visualization and quick learning thanks to its highly interactive commands, with full correlation between displayed data, pictures and plots.
Compatible all types of microarrays made by ex-situ and in-situ techniques.
Reads and analyzes interstitial/staggered/orange packing patterned microarrays made by the Protein NanoPrint, Agilent and others.

Batch processing allows analysis of a large number of microarrays per day to boost productivity (available on Version 3.0.0).
Regular software updates are accessible on line to match evolving needs of customers (updates are free for the 1st year).

Configurable for full or modular automation of:

Scanner control
Configuration saving (scan and analysis parameters)
Bar code reading
Quality control by flagging

Compatible with all industry-standard formats and platforms:

Support GAL files and recordable transcripts in both text and GPR formats.
Images are saved as 16-bit TIFF images with all read parameters and can be copied in JPEG format.
Supports image analysis of 16-bit TIFF files from a variety of other scanners.
Platform-independent and runs on all operating systems (Windows, 32- and 64-bit Linux and Macintosh).

Ordering Information:

Catalog ID

Description

Price (US dollars)*

700A

Simultaneous confocal 2-color fluorescence microarray scanner (635 nm and 532 nm) with Mapix software, computer and monitor, one year warranty, and complimentary software upgrades for one year. Detects Cy3, Alexa 546, Alexa 555, Cy5, Alexa 647, and Alexa 660.

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700R

Confocal single color fluorescence microarray scanner (635 nm) with Mapix software, computer and monitor, one year warranty, and complimentary software upgrades for one year. Detects Cy5, Alexa 647, and Alexa 660.

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700G

Confocal single color fluorescence microarray scanner (532 nm) with Mapix software, computer and monitor, one year warranty, and complimentary software upgrades for one year. Detects Cy3, Alexa 546, and Alexa 555.

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Custom laser configurations are possible. Please contact us directly at arrayit@arrayit.com for more information.

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*Please contact us directly for exact pricing on these products by email at arrayit@arrayit.com or by telephone (408) 744-1331.

*International pricing may vary as much as 30% (or more depending on country) due to import duties, stocking fees and technical support.

Warranty
TeleChem ArrayIt® brand products are sold for research purposes. Extreme care and exact attention should be practiced in the use of the materials described herein. All TeleChem products are subject to extensive quality control and are guaranteed to perform as described when used properly. Any problems with these products should be reported to TeleChem immediately. Our liability is limited to the replacement of the product, or a full refund. Any misuse of this product is the full responsibility of the user, and TeleChem makes no warranty or guarantee under such circumstances.