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Products - Microarrayers - TissueMax™ Automated and Personal Tissue Microarrayers

tissue microarrayers
Arrayit TissueMax™ Automated Tissue Microarrayers provide the market’s finest solutions for high-speed automated preparation of tissue microarrays from many patients including 5 µm positional accuracy, 0.5, 1, 2 and 3 mm tip sizes, two CCD cameras, LED illumination, 10 donor blocks, two recipient blocks, and touch screen computer control. Tissue microarrays (TMAs) possess significant advantages over traditional histological approaches including the analysis of many patient samples simultaneously, complete automation, conservation of precious tissue samples, improved internal experimental control, reduced consumption of antibodies and other reagents, and wide applicability to many molecular techniques including mRNA and protein expression analysis, immunohistochemistry, in situ hybridization, FISH and in situ PCR.

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TissueMax™ Automated Tissue Microarrayer Specifications and Features

  • Automated Tissue Microarrayers
  • Analysis of many patient tissue samples simultaneously
  • Conserves tumors, biopses and other precious biological samples
  • Conserves antibodies and other expensive reagents
  • Improves assay precision through sample and patient multi-plexing
  • Applicable to mRNA and protein expression analysis
  • Miniaturize and automate immunohistochemistry, in situ hybridization, FISH, and in situ PCR
  • High-speed preparation of tissue microarray blocks
  • Maintains tissue integrity during embedding
  • Up to 300 tissues slices per donor block
  • Standardized block configuration simply image analysis
  • Prepare up to 240 tissue cores per hour
  • Core placement success rate >99%
  • Tissue preparation cycle time of 15-18 secs
  • Positional accuracy of 5 µm at donor blocks
  • Fully automated 5 axis computer control
  • Rotary print tip control
  • Three print tip sizes of 1, 2 and 3 mm
  • New 500 µm (0.5 mm) Print Tip Option for 320 (16 x 20) well printing
  • Donor block capacity of 10 blocks
  • Recipient block capacity of 2 blocks
  • Recipient blocks contain 120 x 1 mm wells (10 x 12), 60 x 2 mm wells (6 x 10) and 30 x 3 mm wells (5 x 6)
  • Number of CCD cameras: Two, full color
  • CCD camera chips: 1,280 x 1,024 pixels
  • CCD camera pixel size: 2.2 x 2.2 µm
  • Camera resolution: 5 µm at recipient block and 30 µm at donor block
  • Number of LED illumination modules: Two
  • Complete line of recipient blocks and consumables available
  • Personal computer control with Intel Dual Core 2.2 GHz, 1 GB RAM and 160 GB HD
  • TMM computer operating system and software: Windows XP PRO and Microsoft Excel
  • TMMP computer operating system and software: Windows 7 and Microsoft Excel
  • Computer monitor: touch screen LCD with 15" and 1,024 x 768 pixel display
  • Voltage requirements: 100-120 VAC or 200-240 VAC
  • Power requirements: 1 kilowatt, 10 amps at 110 volts or 5 amps at 220 volts
  • Nominal frequency: 50-60 Hertz
  • Maximum allowable voltage fluctuation: ±10%
  • TissueMax™ instrument weight: 148 kg (325 lbs)
  • TissueMax™ Personal instrument weight: 80 kg (176 lbs)
  • TissueMax™ instrument dimensions (W x D x H): 95 x 70 x 61 cm (37 x 28 x 24”)
  • TissueMax™ Personal instrument dimensions (W x D x H): 75 x 60 x 60 cm (30 x 24 x 24”)
  • Operational temperature range: 10-35°C (50-95°F)
  • Transportion and storage temperature range: 5-55°C (41-131°F)
  • Maximum operational humidity: 80% RH
  • Indoor use only
  • Standard approvals: UL, CE and ISO

Arrayit_TissueMax
Figure 1. TissueMax™ Automated Tissue Microarrayer (Cat. TMM) instrument featuring the most advanced automation technology for the preparation of tissue cores for tissue microarrays. TMM uses an integrated computer and flat panel display to control the instrument operations.

tissue microarrays
Figure 2. TissueMax™ Personal Automated Tissue Microarrayer (Cat. TMMP) instrument featuring the most advanced automation technology for the preparation of tissue cores for tissue microarrays in a compact instrument footprint. TMMP uses a personal computer and screen (included) to control the instrument operations. The new 0.5 mm Print Tip Option (Cat. TMT500) allows the printing of 500 µm tissue cores into 16 x 20 (320) well recipient blocks.

Tissue_microarray
Figure 3. TissueMax™ Automated Tissue Microarrayer removing a tissue core from the tissue donor block. TissueMax™ has a 10 donor block and 2 recipient block capacity, and a 240 core per hour fully automated manufacturing throughput.

Tissue_arrays
Figure 4. TissueMax™ Automated Tissue Microarrayer placing a tissue core into a tissue recipient block. TissueMax™ has a 10 donor block and 2 recipient block capacity, and a 240 core per hour fully automated manufacturing throughput.

Tissue_microarrays
Figure 5. TissueMax™ Automated Tissue Microarrayer tissue core recipient block, containing 30 x 3 mm tissue cores arranged in a 5 x 6 array.

Tissue_Arrayer
Figure 6. TissueMax™ Automated Tissue Microarrayer rotary tissue core sampler containing 1 mm, 2 mm, and 3 mm diameter core print tips arranged on a high precision, computer-controlled rotary arm.

tissue_microarray_block
Figure 7. Tissue core recipient blocks for the TissueMax™ Automated Tissue Microarrayer with 1 mm diameter wells in a 120 well 10 x 12 array (left), 2 mm diameter wells in a 60 well 6 x 10 array (center), and 3 mm wells in a 30 well 5 x 6 array (right). Recipient blocks containing the tissue cores are fitted onto an Arrayit Microtome for sectioning.

microtome
Figure 8. Arrayit TissueMax™ Semi-Automatic Rotary Microtome (Cat. MTM) is a companion instrument for our TissueMax™ Tissue Microarrayers for research and clinical laboratories. The Arrayit Microtome combines tissue sectioning efficiency with a compact footprint and ergonomic design to provide high quality tissue sections from TissueMax™ recipient blocks. A motorized precision feed system ensures fast, safe and smooth recipient block sectioning and a solid base provides optimum stability during use. The integrated precision hand wheel is lockable in 360 degrees and the vertical guide is equipped with cross-roller bearings to prevent operational backlash. An integrated switch panel contains a multi-functional LCD display and precision stepper motors guide coarse recipient block movements by 500 µm and fine recipient block movements from 1-25 µm. Section thickness range is 0.25-50 µm and trimming section thickness range is 1-500 µm. Horizontal and vertical recipient movements are 30 mm and 64 mm, respectively. The recipient block clamp is rotatable in 360 degrees and a quick release system provides convenience and ease-of-use. Arrayit Microtome size dimensions are (L x W x H) 21” x 15” x 11” (53 x 38 x 28 cm), weight 66 lbs (29.8 kg), and 115-230 volts at 50-60 Hz.

tissue arrayers
Figure 9. TissueMax™ Automated Tissue Microarrayer (Cat. TMM) instrument shown in the Arrayit Corporation manfacturing facility (Sunnyvale, CA).

Ordering Information

Product

Description

Cat ID

Price (US dollars)*

TissueMax™ Automated Tissue Microarrayer

Arrayit TissueMax™ Automated Tissue Microarrayers provide the market’s finest solutions for high-speed automated preparation of tissue microarrays from many patients including 5 µm positional accuracy, 1, 2 and 3 mm tip sizes, two CCD cameras, LED illumination, 10 donor blocks, two recipient blocks, and touch screen computer control. Tissue microarrays (TMAs) possess significant advantages over traditional histological approaches including the analysis of many patient samples simultaneously, complete automation, conservation of precious tissue samples, improved internal experimental control, reduced consumption of antibodies and other reagents, and wide applicability to many molecular techniques including mRNA and protein expression analysis, immunohistochemistry, in situ hybridization, FISH and in situ PCR.

TMM

$125,318

TissueMax™ Automated Personal Tissue Microarrayer

Arrayit TissueMax™ Automated Personal Tissue Microarrayers provide the market’s finest solutions for high-speed automated preparation of tissue microarrays from many patients including 5 µm positional accuracy, 1, 2 and 3 mm tip sizes, two CCD cameras, LED illumination, 10 donor blocks, two recipient blocks, BioBlue Personal Computer and 23” LED flat panel display. Tissue microarrays (TMAs) possess significant advantages over traditional histological approaches including the analysis of many patient samples simultaneously, complete automation, conservation of precious tissue samples, improved internal experimental control, reduced consumption of antibodies and other reagents, and wide applicability to many molecular techniques including mRNA and protein expression analysis, immunohistochemistry, in situ hybridization, FISH and in situ PCR.

TMMP

$104,418

TissueMax™ Tissue Microarrayers 500 µm (0.5 mm) Print Tip Option

Arrayit TissueMax™ Tissue Microarrayers 500 µm (0.5 mm) Print Tip Option for TissueMax™ Personal Tissue Microarrayers. The 500 µm (0.5 mm) Print Tip Option (Cat. TMT500) punches and transfers 500 µm diameter 0.5 mm tissue cores from donor blocks to 16 x 20 well recipient blocks for 320 tissue cores per recipient block and 640 tissue cores (2 x 320) per 25 x 76 mm glass substrate slide.

TMT500

$10,505

TissueMax™ Semi-Automated Rotary Microtome

Arrayit TissueMax™ Semi-Automatic Rotary Microtome combines tissue sectioning efficiency and a compact footprint and ergonomic design to provide high quality tissue sections from recipient blocks. A motorized precision feed system ensures fast, safe and smooth recipient block sectioning and a solid base provides optimum stability during use. The integrated precision hand wheel is lockable in 360 degrees and the vertical guide prevents operational backlash. An integrated switch panel contains a multi-functional LCD display and precision stepper motors guide coarse recipient block movements by 500 µm and fine recipient block movements from 1-25 µm. The section thickness range is 0.25-50 µm and the trimming section thickness range is 1-500 µm.

MTM

$20,625

One Year Warranty for TMM

TissueMax™ Automated Tissue Microarrayer One Year Warranties provide comprehensive coverage for normal use and wear of all TMM instrument parts and components except the tissue print tips. Excess wear and misuse may incur additional repair costs.

TMW1

$18,798

Two Year Warranty for TMM

TissueMax™ Automated Tissue Microarrayer Two Year Warranties provide comprehensive coverage for normal use and wear of all TMM instrument parts and components except the tissue print tips. Excess wear and misuse may incur additional repair costs.

TMW2

$31,965

Three Year Warranty for TMM

TissueMax™ Automated Tissue Microarrayer Three Year Warranties provide comprehensive coverage for normal use and wear of all TMM instrument parts and components except the tissue print tips. Excess wear and misuse may incur additional repair costs.

TMW3

$54,285

One Year Warranty for TMMP

TissueMax™ Automated Personal Tissue Microarrayer One Year Warranties provide comprehensive coverage for normal use and wear of all TMMP instrument parts and components except the tissue print tips. Excess wear and misuse may incur additional repair costs.

TPW1

$15,663

Two Year Warranty for TMMP

TissueMax™ Automated Personal Tissue Microarrayer Two Year Warranties provide comprehensive coverage for normal use and wear of all TMMP instrument parts and components except the tissue print tips. Excess wear and misuse may incur additional repair costs.

TPW2

$26,634

Three Year Warranty for TMMP

TissueMax™ Automated Personal Tissue Microarrayer Three Year Warranties provide comprehensive coverage for normal use and wear of all TMMP instrument parts and components except the tissue print tips. Excess wear and misuse may incur additional repair costs.

TPW3

$45,232

TissueMax™ recipient blocks, 320 wells

TissueMax™ recipient blocks, 0.5 mm well diameter, 16 x 20 well pattern, 320 wells per block, 10 blocks per package.

TMX320

$567

TissueMax™ recipient blocks, 120 wells

TissueMax™ recipient blocks, 1 mm well diameter, 10 x 12 well pattern, 120 wells per block, 10 blocks per package.

TMX120

$545

TissueMax™ recipient blocks, 60 wells

TissueMax™ recipient blocks, 2 mm well diameter, 6 x 10 well pattern, 60 wells per block, 10 blocks per package.

TMX60

$523

TissueMax™ recipient blocks, 30 wells

TissueMax™ recipient blocks, 3 mm well diameter, 5 x 6 well pattern, 30 wells per block, 10 blocks per package.

TMX30

$501

For ordering information, technical assistance and shipping schedules please contact us by telephone 408-744-1331 or email arrayit@arrayit.com, or use the purchase buttons to order directly to the Arrayit Store.

*International pricing may vary by as much as 30% or more due to import duties, stocking fees and technical support.

*Add shipping and handling to all orders.

 

 

 

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